drug discovery and development

A pioneering public/private consortium is poised to turn the marathon of drug discovery into a team relay, maybe even a short one.

For decades, scientists have wanted to be able to study dopamine receptors one by one. The brain’s dopamine receptors are responsible for a variety of behaviors, such as reward seeking, and are also involved in psychiatric illnesses like schizophrenia.

Renowned researcher and educator Matthew Jacobson, PhD, has been named the new chair of the UCSF School of Pharmacy’s Department of Pharmaceutical Chemistry. His appointment by Dean B. Joseph Guglielmo, PharmD, will be effective January 15, 2016.

New computer models were able to successfully predict negative side effects for hundreds of currently marketed drugs, report researchers from the UCSF School of Pharmacy, SeaChange Pharmaceuticals, and Novartis Institutes for Biomedical Research in a paper published online this week in the journal...

The new UCSF Center for Quantitative Pharmacology housed within the Department of Bioengineering and Therapeutic Sciences (BTS), a joint department of the Schools of Pharmacy and Medicine, will be inaugurated next week with a wide-ranging, 2-day conference, September 22 and 23, 2011 at William J. ...

Through study results of a particular enzyme of unknown function, called Tm0936, that is found in a bacterium that lives in thermal vents in the Mediterranean Ocean, UCSF School of Pharmacy faculty member Brian Shoichet, PhD and colleagues are shedding light on how to ultimately better predict the...

James A. Wells, PhD, an internationally recognized biochemist and leader in the development of new technologies for engineering proteins and for identifying small molecules to aid drug discovery, has been named chair of the Department of Pharmaceutical Chemistry in the UCSF School of Pharmacy. His...

The odds of finding a chemical compound that can be developed into a drug are not good, says Thomas James, PhD, chair of the UCSF School of Pharmacy's department of pharmaceutical chemistry, but those odds can be improved by university scientists.

UCSF School of Pharmacy faculty member James Wells, PhD, director of the Small Molecule Discovery Center, describes his approach, which uses precise, sophisticated matchmaking techniques, to improving the success rate of finding chemical compounds with the potential to become drugs.

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